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Primary, antagonistic, and integrative hallmarks link molecular damage to systemic aging, helping clarify where therapies like GLP-1s may have a positive influence and which physiological pathways they are most likely to influence [2,3]
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This approach allows the gastrointestinal system to adapt to GLP-1 receptor activation, reducing the incidence and severity of nausea, vomiting, and diarrhea that often accompany rapid dose escalation
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