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Saffron Extract Saffron might seem like an odd ingredient in an appetite support supplement, but there’s actually solid research behind it — specifically for stress-related eating and snacking
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In fact, a quinoxaline (compound 2) and a pyrimidine (compound B) act in an additive manner to activate the GLP-1R under conditions in which the receptor is truncated to remove the N-terminal extracellular domain at which the C-terminus of GLP-1 binds
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