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GLP-1RAs Versus DPP-4is The aggregate crude incidence of thyroid tumors ranged from 0.96 (95% CI 0.90–1.03) to 1.03 (0.91–1.15) per 1,000 person-years in patients initiating GLP-1RAs and 0.94 (0.91–0.97) to 1.13 (1.06–1.20) per 1,000 person-years in patients initiating DPP-4is (Table 2)

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While early studies are promising, more large-scale research is still developing