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Therefore, semaglutide and tirzepatide do not treat: rheumatoid arthritis psoriatic arthritis lupus Sjögren’s syndrome multiple sclerosis inflammatory bowel disease They may improve metabolic inflammation in patients who also have autoimmune disease—but they do not treat the autoimmune condition itself

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Larger and longer-term studies are needed to confirm these findings, and the researchers say they are planning to conduct larger trials soon