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Diarrhea on Zepbound 5mg runs roughly 19% in trials, diarrhea on Zepbound 7.5mg sits between dose tiers, diarrhea on Zepbound 10mg climbs to 21%, and reported rates at 15 mg reach 23%, compared to about 8% on placebo

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Common side effects include mild-to-moderate nausea, reduced appetite (intended), constipation, and occasional vomiting, typically during the first 1-4 weeks of treatment

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