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Timeline: Weeks 1–4: Starting dose (0.25 mg) — minimal weight loss Weeks 5–8: 0.5 mg — noticeable weight loss begins Weeks 12+: 1–2.4 mg — significant weight loss Full effects: 16–20 weeks at target dose.[wegovy] Average weight loss: 15–20% of body weight at 2.4 mg dose.[inlandcosmetic] What Are the Common Side Effects of Semaglutide