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Moreover, adequate safety margins were observed in repeat-dose rat and monkey toxicology studies, which supported advancing PF-06882961 to human clinical studies
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Tirzepatida se asoció a cambios en la puntuación de actividad de la esteatohepatitis y sus componentes individuales (esteatosis, inflamación lobular y balonamiento hepatocelular) y hubo una disminución en la cuantificación de grasa hepática y biomarcadores séricos
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