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He also explained that certain medications, such as pain relievers (Ibuprofen) and anti-inflammatory drugs (NSAIDs) may interact negatively with Ozempic, so it’s best to avoid them while taking the weight loss drug

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The largest trial to date, the phase 3 TRIUMPH-1 (~2,339 people), put average weight loss at the top dose at 28.3% over 80 weeks, climbing to 30.3% by two years in an extension group, with knee-arthritis pain and sleep-apnea events both dropping sharply