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The Ominous Octet Over the last 30 years our understanding of the pathophysiology of T2DM has revealed that the disease is more complicated than previously appreciated with at least 8 distinct pathogenic abnormalities which collectively comprise the OMINOUS OCTET (2) (Figure 1)
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( A ) The intrinsic potency of TZP ( n = 23) in the presence of casein (CAS) is equivalent to GIP(1-42) ( n = 49)
